Top 17 Best pet cleaners with enzymes in 2022

There have been a lot of choices for the pet cleaners with enzymes, and finding the one that’s right for you has proved difficult. It’s hard to choose one, but this list will guide you through making an informed decision based upon what you desire from it and how much you’re pleasant to spend.

All of these pet cleaners with enzymess under are not bound by contracts and they will still work when you buy them through our website. This saves you money because Amazon isn’t getting any commissions upon your purchase since you’re coming directly to us.

Followings are the best-selling pet cleaners with enzymes on Amazon:

Our extensive selection of rotate models will put taking place to you locate the perfect pet cleaners with enzymes.

Best pet cleaners with enzymes

In this article, we have compiled a list of the most popular pet cleaners with enzymes. Some common features are in addition to included in each description, so you can make an informed purchase decision much more easily!

1
Simple Solution Pet Stain and Odor Remover | Enzymatic Cleaner with 2X Pro-Bacteria Cleaning Power | 32 Ounces
  • REMOVES PET STAINS- Simple Solution Stain & Odor Remover is formulated to eliminate and neutralize tough dog and cat stains and odors like urine, feces, and vomit
  • UNIQUE PRO-BACTERIA FORMULA - This stain and odor remover has a unique Pro-Bacteria and enzyme formula that eliminates stains and odors, and helps prevent repeat marking
  • MULTIPLE USES - Safely removes dog and cat stains and odors from carpet, upholstery, bedding, fabric toys, clothing, and other water-safe surfaces in your home
  • VERSATILE CLEANING - Our patented 3-in-1 nozzle sprayer gives you more options to tackle stains and odor: stream, foam, or mist
2
Rocco & Roxie Stain & Odor Eliminator for Strong Odor - Enzyme-Powered Pet Odor Eliminator for Home - Carpet Stain Remover for Cats and Dog Pee - Enzymatic Cat Urine Destroyer - Carpet Cleaner Spray
  • CERTIFIED GENTLE AND SAFE Chlorine free and color safe. Safe to use around pets and children. No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (CRI)
  • ELIMINATES STAINS, ODORS AND RESIDUE If it’s gross, it’s gone. Not just the stain, but the stink. From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all.
  • EVERY SURFACE, EVERY TIME For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen.
  • ENZYME ACTIVATED The key is getting to the problem deep-down. This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated.
  • 100% SATISFACTION GUARANTEED An Amazon best seller—for a reason. If your stains and odors aren’t gone, neither is your money. We’ll refund it in full.
Sale3
Angry Orange Enzyme Cleaner & Pet Stain Remover Spray - 32oz Pet Odor Eliminator for Home, Carpet, and Floor - Cat and Dog Urine Destroyer (Fresh Citrus Scent) 
  • Enjoy all the furry love without the nasty messes! Our enzyme-active pet stain and odor remover can tackle any stubborn stains and foul smells, including pet urine, feces, and even vomit.
  • This isn't just another pet spray that masks the bad odors and stains. Our floor & carpet odor eliminator destroys them with enzymes that activate upon contact and ensure 80 hours of freshness.
  • Discover an enzyme cleaner that can clean it all! Our solution is a pet cleaner for carpet, hardwood floors, tile, litter boxes, pillows, kennels, and more.
  • Made with enzymes and natural ingredients, this odor & urine remover for dogs and cats will leave a subtle orange scent behind without the use of harsh ingredients.
  • We care about making a great enzymatic cleaner with the strength to destroy messes, and keeping you and your pets happy. If you have any questions or concerns, our customer support is available 24/7.
4
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain Remover | Remove Dog Cat Urine Smell from Carpet, Rug or Hardwood Floor and Other Surfaces (Gallon)
  • BEST PROFESSIONAL GRADE CLEANING SOLUTION: Scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring, upholstery, area rugs and carpets, yet safe to use around kids and pets. Permanently destroys pet enzyme odors and stains
  • PET STAIN AND ODOR MIRACLE: Bubba's uses natural dormant enzymes that become active upon hitting that strong smelling cat pee, billions of enzymes destroy stains down to the carpet pad. Competitors use active enzymes that die off and lose effect
  • SATISFACTION GUARANTEED: Other pet odor enzyme sprays use active enzymes that are ineffective soon after you buy them. Bubba's dormant enzyme formula is the best premium deep cleaning stain and pet urine enzyme carpet cleaner or YOUR MONEY BACK
  • CARPET & RUG INSTITUTE CERTIFIED: Our Pet Pee Cleaner and Enzymatic Odor Remover is a Top Rated pet stain & odor miracle. Don't be disappointed by other brands pet cleaner sprays. Try Bubbas pet enzyme treatment cleaner instead
  • MANY USES: Our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and more. Use to remove shoe odor, clean auto carpeting stains, use as clothes pretreat for removal of tough set in grass stains. litter box cleaner, or on furniture to remove odors
5
BUBBAS Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic Stain Remover | Remove Dog Cat Urine Smell from Carpet, Rug or Hardwood Floor and Other Surfaces (64oz)
  • BEST PROFESSIONAL GRADE CLEANING SOLUTION: Scientifically formulated to be more potent than other pet odor enzyme cleaners for your flooring, upholstery, area rugs and carpets, yet safe to use around kids and pets. Permanently destroys pet enzyme odors and stains
  • PET STAIN AND ODOR MIRACLE: Bubba's uses natural dormant enzymes that become active upon hitting that strong smelling cat pee, billions of enzymes destroy stains down to the carpet pad. Competitors use active bacteria that die off and lose effect
  • SATISFACTION GUARANTEED: Other pet odor enzyme sprays use active enzymes that are ineffective soon after you buy them. Bubba's dormant enzymes formula is the best premium deep cleaning stain and pet urine enzyme carpet cleaner or YOUR MONEY BACK
  • CARPET & RUG INSTITUTE CERTIFIED: Our Pet Pee Cleaner and Enzymatic Odor Remover is a Top Rated pet stain & odor miracle. Don't be disappointed by other brands pet cleaner sprays. Try Bubbas pet enzyme treatment cleaner instead
  • MANY USES: Our enzyme based stain remover and cleaning solution can be used in all areas of your house, auto, kitchen, bathroom, laundry room and more. Use to remove shoe odor, clean auto carpeting stains, use as clothes pretreat for removal of tough set in grass stains. litter box cleaner, or on furniture to remove odor
Sale6
Pet Stain & Odor Miracle - Enzyme Cleaner for Dog Urine Cat Pee Feces Vomit, Enzymatic Solution Cleans Carpet Rug Car Upholstery Couch Mattress Furniture, Natural Eliminator (S/M 32FL OZ)
  • ❤️ EASY CLEANUP - Pet Stain & Odor Miracle makes clean up fast and easy, so you can quickly return to having fun with your fur-baby. Only an enzyme-based cleaning solution can completely remove 100% of organic matter, such as urine, feces, vomit, blood, and drool (chemical based cleaners cannot do that). All of our products smell incredible!
  • 😊 INCREDIBLE VALUE - Pet Stain & Odor Miracle makes it very easy for you to clean every surface in your home - carpet, rug, hardwood, laminate, tile, concrete floor, furniture, mattress, leather, couch, pet beds, crates, litter box, car upholstery and mats. You can even use this amazing enzymatic solution outside, in artificial grass and turf, patio, deck and virtually any other surface.
  • ⭐ HIGHEST QUALITY - All of Sunny & Honey’s products are made with the highest quality ingredients available, right here - in the beautiful USA. As a hardworking family-run small business, we wholeheartedly believe in providing you with the absolute best products and value. We take this responsibility seriously!
  • 🌱 NATURAL CLEANING POWER - Pet Stain & Odor Miracle was created with your furry kids in mind! This bio-enzymatic formula is biodegradable, non-toxic, and is scented with essential oils. This spray solution is also Leaping Bunny Certified. We love animals and nature - let’s protect them together!
  • ✔ OUR PROMISE - If you are not 100% in LOVE with Pet Stain & Odor Miracle, send it back for a full refund. You have absolutely nothing to lose (except a stain or two) . Click “Add To Cart” Right Now!
7
Simple Solution Cat Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 32 Ounces
  • DESIGNED FOR THE TOUGHEST ODORS AND ORGANIC STAINS- Simple Solution pet Extreme Stain and Odor remover is three times stonger than our regular formula to eliminate tough dog and cat odors and stains.
  • PROFESSIONAL STRENGTH FORMULA - Extreme Stain and Odor Remover is a professional strength Pro-Bacteria and enzyme formula that breaks down and eliminates stains and odors.
  • SPECIFICALLY FOR PET ODORS AND ORGANIC STAINS - Safely and quickly removes dog and cat urine, feces, and vomit on carpet, upholstery, bedding, fabric toys, clothing, or other water-safe surfaces in your home
  • NEW PATENTED MULTI-FUNCTIONAL SPRAYER - Now designed with a new patented 3-in-1 nozle sprayer (foam, mist, and stream).
8
Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain & Odor Remover - Plant Based, Safe, Multi-Purpose/Surface Eliminator: Floors, Laundry, Drain, Carpet; Urine, Wine, Smoke, Vomit, Coffee - No Rinse Formula - Dye Free (Gallon - 128oz)
  • ENZYME ACTIVATED: Our enzymatic formula contains natural live cultures that seek & destroy organic waste as a food source. Releasing powerful enzymes to break down complex compounds for the probiotics to consume, they remain active for up to 80 hrs, continuing to work against new soils & odors as they emerge. Unlike traditional chemical-based products, these probiotics penetrate small cracks & grout, eliminating stains & odors. Simply spray & let the probiotics do the dirty work!
  • THE SCIENCE: Enzymes work to break down complex waste particles into smaller pieces that can be more easily consumed. These smaller particles—organic wastes, urine, grease, stains—become “food” for Probiotics to digest and break down into two basic compounds—carbon dioxide (CO2) and water (H2O).
  • READY TO USE & NO RESIDUE: Commercial-grade, maximum strength formula provides fast-acting, sustained stain & odor elimination that’s RELIABLE & EASY. No need to measure, mix, or dilute; just saturate and give your hungry Bio-Enzyme army time to eat. With safe ingredients, rinsing is not necessary. Bastion will not leave behind any haziness, film, streaks, stickiness, buildup, or residue. All you’ll have is a clean, odor-free environment - without that nasty using dangerous and harsh chemicals.
  • MULTI-SURFACE: Formulated for efficiency & versatility, Bastion’s Probiotic Stain & Odor Remover can be used on hard surfaces, floors, carpets, fabric, laundry, drains, grease traps, toilets, septic tanks, & more, to effectively eliminate stains and odors at their source. Designed to rapidly destroys organic soils and rid odors completely and permanently so they never return, Bastion is your #1 solution for cleaning grease, food stains, wine, coffee, urine, feces, blood, and vomit.
  • FAMILY SAFE & ENVIRONMENTALLY FRIENDLY: Bastion Probiotic Stain & Odor Remover contains neither bleach nor chlorine. This product is non-toxic and hypoallergenic, making it safe for your children, pets, home, and the planet. With its water-based formula, it’s tough on stains & odors, while gentle on people and objects. Use it freely around your home with peace of mind and enjoy the fresh & clean environment that Bastion provides.
9
Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator | Urine Odor Remover | Pet Urine Enzyme Cleaner | Pet Stain and Odor Remover | Enzymatic Cleaner for Dog Urine and Cat Urine
  • ✔️ Scientifically Formulated Stain & Odor Eliminator: Removes the stain and stink from your pets
  • ✔️ Enzyme Powered: Completely removes all pet stains and odors for urine, feces, vomit & drool.
  • ✔️ Child & Pet Safe: Natural enzyme formula is the safest way to remove pet stains and odors.
  • ✔️Multi Surface: Use on carpet, wood, furniture, rugs, crates, upholstery, outdoor carpets etc.
  • ✔️ 100% Guaranteed-Proudly Made In The USA: If you're not 100% HAPPY, we will refund it in full
10
PetSafe Wee Care Pet Loo Enzyme Cleaner 100% Biodegradable Chemical Free Erases Stains and Odors, PAC00-14492, 16-Ounce,Clear
  • ECO-FRIENDLY: Safe for people, pets and the planet
  • ELIMINATES ODORS AND STAINS: This enzyme-based cleaner washes away dirt and residue.
  • 100% BIODEGRADABLE: Enzyme-based cleaner with safe, natural ingredients
  • CHEMICAL FREE: Non-toxic and non-irritating for your dog’s safety and your peace of mind; made in the USA
  • MULTIPLE USES: Use Wee Care for the Pet Loo, synthetic grass, cat litter pans, outdoor toileting areas, carpet, upholstery and more
Sale11
Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine, Feces, Blood, Vomit - 32oz
  • Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
  • Use on carpets, rugs, pet bedding, upholstery, clothing, curtains, Auto upholstery, litter boxes, crates and carriers, tile, finished wood, laminates, concrete and more
  • Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
  • Safe for use around pets
  • Eliminates new, old and set-in stains
12
Simple Green Bio Dog Active Stain & Odor Remover - Enzyme Cleaner & Stain Remover for Carpet, Rugs & Fabric – eliminates Urine Odor (32 oz Spray & 1 gal Refill)
  • Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
  • Use on porous surfaces such as carpet, rugs, pet bedding, fabric, upholstery, clothing, curtains, Auto upholstery, crates, tile, finished wood, laminates, concrete and more
  • Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
  • Safe for use around pets
  • Eliminates new, old and set-in stains
13
Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 1 Gallon - Lavender Breeze
  • Pro Grade Clean - Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most effective cleaning products to get the job done. Whether you’re a pro or just expect pro-grade results, Zeiff delivers Pro Grade Clean
  • Powerful Cleaning Performance - Our proprietary formulation breaks up complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease and grime without leaving any visible residue. Don't just expect clean, expect Zeiff Clean! You'll know it when you see it, clean you didn't even know exists
  • Multi-Purpose Enzyme Cleaner - The special blend of bacterial enzymes, detergent and deodorant, prevents clogging in drains, grease traps, septic tanks, drain lines and downpipes, and cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and much more. Ideal for Professional and Home use
  • Deodorizer & Odor Eliminator - Highly concentrated bacterial digestant for grease, stains, oils, & organic waste. Effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage and grease, leaves long-lasting freshness, with a subtle lavender breeze that instantly refreshes any space with a pleasant aroma
  • Safe & Effective - Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral, paraben-free, pet safe, cruelty-free. Proudly made in the USA
14
Simple Solution Pet Urine Destroyer | Enzymatic Cleaner with 2X Pro-Bacteria Cleaning Power | Targets Urine Stains and Odors | 1 Gallon
  • TOUGH ON URINE - Simple Solution Pet Urine Destroyer combines Pro-Bacteria and Enzymes in a formula that neutralizes the toughest urine odors and discourages future marking.
  • ELIMINATE STAINS – Simple Solution’s enzymatic cleaner technology lifts urine stains leaving your carpet stain and odor free.
  • MULTIPLE USES – Our pet odor and stain remover is safe to use on carpet, upholstery, bedding, fabric toys, clothing and other water-safe surfaces in your home when used as directed.
  • CARPET SAFE – Certified by the Carpet and Rug Institute, our Pet Urine Destroyer is safe to use on all colorfast carpets when used as directed.
  • SAFE FOR THE HOME – Simple Solution pet urine remover is safe for use around pets and your household when used as directed.
15
Naturally It's Clean Floor Enzyme Floor Cleaner | Safer For Pets and Kids | Powerful Plant Based Enzyme Formula Cleans Hardwood, Tile, and Floors Stain Free | 24 Gallon Rinse Free Concentrate | 1 Pack
  • ONE BOTTLE MAKES 24 GALLONS OF DIRT CUTTING, NATURAL ALL PURPOSE CLEANER | Our plant based enzyme formulation is specifically designed to rapidly biodegrade natural soils into its basic elements for easy and effective cleaning. And with regular use, continues to break down dirt even after each application. No rinsing required.
  • SAFE ON ALL HARD FLOORS AND SURFACES | Biodegradable formula will not damage floors or any surface. It is safe to use as wood and hardwood floor cleaner, laminate floor cleaner, vinyl floor cleaner, safe on garage floor tiles, stone, marble, concrete, bathroom floors.
  • ELIMINATES STUBBORN, LINGERING ODORS | Our enzyme's powered formula effectively breaks down organic material that causes odors, leaving only a natural fresh clean smell. You can use our natural enzyme cleaner in floor jet cleaners.
  • EASY TO USE | Just mix 1 oz of our concentrated enzyme floor cleaner liquid for every gallon of water. Use a wipe, spray bottle, or mops to apply the cleaning solution to any surface, and watch the enzymes work! No rinsing is required as it does not leave film or residue so you can save on an expensive rinse kit for heavy cleaning. It is a non-caustic cleaner that is safer for use around pets and children.
  • THE ENZYME SOLUTIONS GUARANTEE | As the foremost expert in advanced natural enzyme technology, our environmentally safer products are formulated with the highest potency for maintaining quality and effectiveness. These formula contains: No Parabens. No Artificial Dyes. No Alcohol & Ammonia. No Sulfates. No Artificial Fragrances. No Phosphates. No Petroleum. No SLS. No Bleaching Agents.
16
TriNova Natural Pet Stain and Odor Remover Eliminator - Advanced Enzyme Cleaner Spray - Remove Old & New Pet Stains & Smells for Dogs & Cats - All-Surface Safe - 32 OZ
  • ✅ 100% NATURAL CLEANER - We are setting the "Green Standard' by using only natural and organic ingredients in our formula and listing everything right on the label.
  • ✅ PROFESSIONAL STRENGTH - TriNova's Pet Stain & Odor Remover features a blend of natural enzymes that tackle stains and odors at their root to clean and neutralize. The enzymes work to break down the stains, drying out and disintegrating when they're finished to restore your carpet to like-new condition.
  • ✅ SAFE Around Kids & Pets - TriNova understands your pets frequent the spaces where you and your children spend the most time as well. Because of this, TriNova's Pet Stain & Odor Remover contains a formula that leaves surfaces safe for your kids to keep on playing without any worry about harmful chemicals or toxins.
  • ✅ USE IT ANYWHERE - Use this natural pet stain remover on most surfaces such as bedding, mattress, cage, kennel, laundry, clothes, hardwood, litter box and more. Even use it for small animals like hamsters, rat, and mice cages
  • ✅ 100% SATISFACTION GUARANTEE - We think you'll love our product, but if you don't just let us know and we'll refund your purchase price!
Sale17
Simple Solution Cat Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 32 Ounces
  • DESIGNED FOR CAT MESSES - Simple Solution Cat Extreme Stain and Odor Remover is specifically formulated to eliminate tough cat odors and stains, such as urine, feces, and vomit, while discouraging repeat spraying.
  • TRIPLE THE CLEAN- The 3X cleaning formula is specifically designed to remove tough stains and odor from carpets, bedding, fabric, and most water-safe surfaces.
  • STRONGER AND BETTER - The professional strength formula of our Simple Solution Cat Extreme Stain & Odor Remover breaks down organic cat messes and is safe around children and pets when used as directed.
  • NEW PATENTED MULTI-FUNCTIONAL SPRAYER - Now designed with a new patented 3-in-1 nozzle sprayer (foam, mist, and stream).
  • MADE IN THE USA - Simple Solution Cat Extreme Stain and Odor Remover is proudly manufactured in the USA.

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